Amphetamine is understood to inhibit monoamine oxidase, Whilst the power of amphetamine and its metabolites to inhibit different P450 isozymes and also other enzymes has not been adequately elucidated. In vitro experiments with human microsomes indicate insignificant inhibition of CYP2D6 by amphetamine and slight inhibition of CYP1A2, 2D6, and 3A4

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